SLC27A6

Across TCGA cell cohorts, SLC27A6 mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC27A6-associated genes across cancer lineages are CD300H, ASZ1, and S100G. Each is linked with SLC27A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC27A6-to-partner and partner-to-SLC27A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by SLC27A6-low versus SLC27A6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A6→partner) and Y-score (partner→SLC27A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.022	+3.192	<.001	.002	3	2
BLOOD_Leukemia	ASZ1 →	+0.132	+4.152	<.001	.009	3	2
CNS	S100G →	+0.203	+4.321	<.001	.009	3	1
CNS	GPR149 →	+0.011	+4.321	.003	.009	3	1
LUNG_SCLC	BPIFB6 →	+0.012	+5.029	.001	.006	3	1
LUNG_SCLC	OR2T4 →	+0.083	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

CD300H by SLC27A6 expression — LARGE_INTESTINE

Explore this box plot interactively →