SLC27A4

Across TCGA pan-cancer cohorts, SLC27A4 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC27A4 data layer compared with 22 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SLC27A4 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC27A4 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

UCEC, SKCM, and LGG are the cancer types where SLC27A4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.829	.016	26	view →
SKCM	DFS	Median	III,IV	1.000	0.235	.005	15	view →
LGG	OS	Median	All	0.182	0.909	<.001	12	view →
LUSC	OS	Median	II,III,IV	0.172	0.732	.003	12	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC27A4–UCEC (DFS)

Open the UCEC breakdown →