SLC27A4

Across TCGA patient cohorts, SLC27A4 mutation is significantly associated with the RNA expression of many other genes, with 1,935 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC27A4-associated genes across cancer lineages are MIR8053, RNU4-31P, and RNU6ATAC30P. Each is linked with SLC27A4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC27A4-to-partner and partner-to-SLC27A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8053 grouped by SLC27A4-low versus SLC27A4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A4→partner) and Y-score (partner→SLC27A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR8053 →	+0.300	+4.757	<.001	.004	3	4
CESC	RNU4-31P →	+0.222	+3.874	.001	.006	3	2
CESC	RNU6ATAC30P →	+0.353	+4.006	.003	.006	3	2
CESC	EPPIN-WFDC6 →	+0.152	+3.975	.004	.006	3	2
CESC	MTND4LP24 →	+0.076	+5.579	<.001	.001	3	2
CESC	MIR4757 →	+0.390	+5.729	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,935 associations by consensus.

MIR8053 by SLC27A4 expression — CESC

Explore this box plot interactively →