SLC27A4

Across TCGA cell cohorts, SLC27A4 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC27A4-associated genes across cancer lineages are GIMAP7, LCE2A, and OR4D10. Each is linked with SLC27A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC27A4-to-partner and partner-to-SLC27A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GIMAP7 grouped by SLC27A4-low versus SLC27A4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A4→partner) and Y-score (partner→SLC27A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GIMAP7 →	+0.032	+3.807	.004	.007	3	1
LUNG_NSCLC_LUAD	LCE2A →	+0.032	+4.189	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR4D10 →	+0.031	+4.078	<.001	.009	3	1
LARGE_INTESTINE	NLRC3 →	+0.145	+3.266	<.001	.005	3	1
LARGE_INTESTINE	DAZ1 →	+0.528	+3.080	.004	.004	3	1
LARGE_INTESTINE	RPTN →	+0.880	+3.762	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

GIMAP7 by SLC27A4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →