SLC27A3

Across TCGA pan-cancer cohorts, SLC27A3 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SLC27A3 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SLC27A3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC27A3 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

COAD, UCEC, and HNSC are the cancer types where SLC27A3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.912	1.000	.014	36	view →
UCEC	DFS	Median	All	0.768	0.963	.002	14	view →
HNSC	OS	Median	IV	0.870	0.604	.008	7	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.321	.006	7	view →
PDAC	OS	Tertile	III,IV	0.500	1.000	.022	3	view →
LUAD	DFS	Median	III,IV	1.000	0.498	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SLC27A3–COAD (DFS)

Open the COAD breakdown →