SLC27A3

Across TCGA patient cohorts, SLC27A3 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC27A3-associated genes across cancer lineages are CD31, JNK_pT183_Y185, and EGFR_pY1068. Each is linked with SLC27A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC27A3-to-partner and partner-to-SLC27A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD31 grouped by SLC27A3-low versus SLC27A3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A3→partner) and Y-score (partner→SLC27A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD31 →	-0.170	-2.999	.017	.035	3	3
UCEC	JNK_pT183_Y185 →	-0.175	-2.446	.031	.020	3	2
UCEC	EGFR_pY1068 →	-0.264	-3.000	.029	.036	3	1
UCEC	GATA6 →	-0.230	-3.000	.004	.035	3	1
UCEC	INPP4B →	-0.386	-3.321	.013	.010	3	1
UCEC	MEK1 →	+0.468	+3.584	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

CD31 by SLC27A3 expression — UCEC

Explore this box plot interactively →