SLC27A3

Across TCGA cell cohorts, SLC27A3 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC27A3-associated genes across cancer lineages are OR6V1, MDGA2, and SLC25A52. Each is linked with SLC27A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC27A3-to-partner and partner-to-SLC27A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6V1 grouped by SLC27A3-low versus SLC27A3-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A3→partner) and Y-score (partner→SLC27A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR6V1 →	+0.016	+3.662	<.001	.001	3	2
LARGE_INTESTINE	MDGA2 →	+0.116	+2.591	<.001	.008	3	1
LARGE_INTESTINE	SLC25A52 →	+0.057	+3.567	.008	.002	3	1
LARGE_INTESTINE	VAX1 →	+0.556	+2.782	.001	.007	3	1
LARGE_INTESTINE	ITGAD →	+0.009	+3.510	<.001	<.001	3	1
LARGE_INTESTINE	SSMEM1 →	+0.021	+2.707	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

OR6V1 by SLC27A3 expression — STOMACH

Explore this box plot interactively →