SLC27A2

Across TCGA pan-cancer cohorts, SLC27A2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SLC27A2 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC27A2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC27A2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and COAD show a favorable association.

CCRCC, COAD, and HNSC are the cancer types where SLC27A2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.883	0.590	<.001	99	view →
COAD	DFS	Median	All	1.000	0.887	.022	18	view →
HNSC	DFS	Quartile	II,III,IV	0.867	0.542	.006	14	view →
LSCC	DFS	Median	II,III,IV	0.838	0.574	.011	12	view →
PDAC	DFS	Median	IV	0.934	0.250	.024	5	view →
GBM	DFS	Tertile	All	0.887	0.698	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SLC27A2–CCRCC (DFS)

Open the CCRCC breakdown →