SLC27A2

Across TCGA patient cohorts, SLC27A2 mutation is significantly associated with the RNA expression of many other genes, with 1,585 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC27A2-associated genes across cancer lineages are TRIM60P19, ZNF232-AS1, and FAM43B. Each is linked with SLC27A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC27A2-to-partner and partner-to-SLC27A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM60P19 grouped by SLC27A2-low versus SLC27A2-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A2→partner) and Y-score (partner→SLC27A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM60P19 →	+0.063	+5.149	<.001	.007	3	2
SKCM	ZNF232-AS1 →	+0.533	+3.334	.007	.005	3	2
UCEC	FAM43B →	-0.765	-4.000	.004	<.001	3	2
UCEC	PNMA3 →	-1.149	-2.906	.008	.002	3	2
SKCM	ADRA2C →	-1.573	-2.906	<.001	.001	3	2
UCEC	SLIT3 →	-0.916	-2.906	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,585 associations by consensus.

TRIM60P19 by SLC27A2 expression — GBM

Explore this box plot interactively →