SLC27A2

Across TCGA patient cohorts, SLC27A2 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC27A2-associated genes across cancer lineages are FASN, eEF2, and IGFBP2. Each is linked with SLC27A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC27A2-to-partner and partner-to-SLC27A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by SLC27A2-low versus SLC27A2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A2→partner) and Y-score (partner→SLC27A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	FASN →	+0.536	+2.459	.022	.020	3	2
UCEC	eEF2 →	+0.474	+2.000	.003	.032	3	2
UCEC	IGFBP2 →	-0.921	-2.000	.001	.032	3	2
SKCM	ACVRL1 →	+0.135	+2.459	.042	.020	3	1
SKCM	NF2 →	-0.283	-3.000	.023	.035	3	1
SKCM	AMPK_alpha →	+0.164	+3.000	.014	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

FASN by SLC27A2 expression — SKCM

Explore this box plot interactively →