SLC27A2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC27A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,284 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC27A2-associated GO terms across cancer lineages are Positive regulation of nitric-oxide synthase activity, Establishment of epithelial cell apical/basal polarity, and Water-soluble vitamin biosynthetic process. Each is linked with SLC27A2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC27A2-to-partner and partner-to-SLC27A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of nitric-oxide synthase activity grouped by SLC27A2-low versus SLC27A2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A2→partner) and Y-score (partner→SLC27A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCPositive regulation of nitric-oxide synthase activity →+1.014+1.451<.001.001310
URINARY_TRACTEstablishment of epithelial cell apical/basal polarity →-0.208-2.165<.001.001310
LUNG_SCLCWater-soluble vitamin biosynthetic process →+0.199+2.068<.001<.001310
URINARY_TRACTCopper ion export →-0.175-2.105<.001.00139
BLOOD_LymphomaPositive regulation of blood-brain barrier permeability →+0.735+1.935.001.00138
BONERNA import into mitochondrion →+0.185+0.578<.001.00438
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,284 associations by consensus.

Positive regulation of nitric-oxide synthase activity by SLC27A2 expression — LUNG_SCLC

Box plot of Positive regulation of nitric-oxide synthase activity in SLC27A2-low vs SLC27A2-high samples in LUNG_SCLC.

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Exploration