SLC27A2

Across TCGA cell cohorts, SLC27A2 mutation is significantly associated with the drug of many other genes, with 37 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC27A2-associated genes across cancer lineages are Fulvestrant, 123829, and Sabutoclax. Each is linked with SLC27A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC27A2-to-partner and partner-to-SLC27A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fulvestrant grouped by SLC27A2-low versus SLC27A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A2→partner) and Y-score (partner→SLC27A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Fulvestrant →	+0.363	+2.649	.034	.046	3	1
LARGE_INTESTINE	123829 →	+0.646	+2.649	.026	.046	3	1
LARGE_INTESTINE	Sabutoclax →	+0.579	+2.769	.005	.040	3	1
LARGE_INTESTINE	GSK429286A →	+0.308	+2.652	.049	.045	3	1
LARGE_INTESTINE	WZ3105 →	+0.792	+2.652	.021	.045	3	1
LARGE_INTESTINE	Masitinib →	+0.548	+2.652	.010	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Fulvestrant by SLC27A2 expression — LARGE_INTESTINE

Explore this box plot interactively →