SLC27A1

Across TCGA pan-cancer cohorts, SLC27A1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SLC27A1 data layer compared with 21 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher SLC27A1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC27A1 expression acts as an unfavorable survival marker.

OV, BRCA, and ACC are the cancer types where SLC27A1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	II,III,IV	0.193	0.541	.013	18	view →
BRCA	OS	Median	II,III,IV	0.434	0.913	.002	18	view →
ACC	OS	Median	All	0.118	0.624	.038	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	OS	Median	III,IV	0.301	0.704	.017	6	view →
READ	OS	Median	All	0.281	0.830	.006	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SLC27A1–OV (DFS)

Open the OV breakdown →