SLC27A1

Across TCGA pan-cancer cohorts, SLC27A1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SLC27A1 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SLC27A1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC27A1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

LSCC, UCEC, and COAD are the cancer types where SLC27A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	II,III,IV	0.648	1.000	.007	29	view →
UCEC	DFS	Quartile	III,IV	0.269	1.000	.013	22	view →
COAD	DFS	Tertile	All	0.923	1.000	.039	6	view →
PDAC	OS	Median	II,III,IV	0.967	0.739	.002	5	view →
HNSC	DFS	Quartile	II,III,IV	0.891	1.000	.008	5	view →
GBM	OS	Median	All	0.684	0.415	.003	4	view →
CCRCC	DFS	Median	IV	0.253	0.749	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SLC27A1–LSCC (OS)

Open the LSCC breakdown →