SLC27A1

Across TCGA patient cohorts, SLC27A1 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC27A1-associated genes across cancer lineages are GAPDH, Rad50, and ATM. Each is linked with SLC27A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC27A1-to-partner and partner-to-SLC27A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by SLC27A1-low versus SLC27A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A1→partner) and Y-score (partner→SLC27A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.462	+2.459	.014	.018	3	2
UCEC	Rad50 →	-0.285	-2.000	<.001	.003	3	2
UCEC	ATM →	-0.503	-1.906	.001	.015	3	2
UCEC	Caspase-7-cleavedD198 →	+0.475	+3.321	.023	.009	3	2
UCEC	4E-BP1 →	+0.263	+2.459	.005	.018	3	2
UCEC	Di-Ras3 →	-0.131	-1.362	.012	.037	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

GAPDH by SLC27A1 expression — UCEC

Explore this box plot interactively →