SLC27A1

Across TCGA cell cohorts, SLC27A1 mutation is significantly associated with the RNA expression of many other genes, with 642 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC27A1-associated genes across cancer lineages are FBXW10, GPR3, and GIMAP7. Each is linked with SLC27A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC27A1-to-partner and partner-to-SLC27A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FBXW10 grouped by SLC27A1-low versus SLC27A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC27A1→partner) and Y-score (partner→SLC27A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FBXW10 →	+0.192	+3.562	<.001	<.001	3	2
LARGE_INTESTINE	GPR3 →	+0.855	+2.628	<.001	.002	3	2
CNS	GIMAP7 →	+0.054	+4.169	<.001	.008	3	1
CNS	SMIM28 →	+0.034	+4.321	.004	.009	3	1
LUNG_NSCLC_LUAD	MS4A13 →	+0.325	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR4C12 →	+0.022	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 642 associations by consensus.

FBXW10 by SLC27A1 expression — LARGE_INTESTINE

Explore this box plot interactively →