SLC26A9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC26A9 mutation is significantly associated with the RNA expression of many other genes, with 3,995 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A9-associated genes across cancer lineages are RPS27P26, OR52Z1, and MIR6081. Each is linked with SLC26A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC26A9-to-partner and partner-to-SLC26A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS27P26 grouped by SLC26A9-low versus SLC26A9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A9→partner) and Y-score (partner→SLC26A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRPS27P26 →+0.099+1.861<.001.00133
COADOR52Z1 →+0.061+3.917<.001.00933
LIHCMIR6081 →+0.308+4.014<.001.00432
LIHCRNU6-519P →+0.343+3.776<.001.00732
LIHCHSD17B7P1 →+0.038+4.853<.001<.00132
CESCSPATA8-AS1 →+0.210+4.969<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,995 associations by consensus.

RPS27P26 by SLC26A9 expression — UCEC

Box plot of RPS27P26 in SLC26A9-low vs SLC26A9-high samples in UCEC.

Explore this box plot interactively →

Exploration