SLC26A9

Across TCGA cell cohorts, SLC26A9 mutation is significantly associated with the RNA expression of many other genes, with 183 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC26A9-associated genes across cancer lineages are OR4F5, PPCS, and NDUFS4. Each is linked with SLC26A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC26A9-to-partner and partner-to-SLC26A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F5 grouped by SLC26A9-low versus SLC26A9-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A9→partner) and Y-score (partner→SLC26A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR4F5 →	+0.040	+4.196	<.001	.006	3	2
LARGE_INTESTINE	PPCS →	+0.382	+2.265	.007	.001	3	2
LARGE_INTESTINE	NDUFS4 →	+0.446	+3.234	.004	.004	3	2
KIDNEY	TAS2R60 →	+0.033	+5.000	<.001	.005	3	1
CNS	TEX55 →	+0.037	+4.321	<.001	.009	3	1
CNS	KRTAP19-4 →	+0.139	+4.754	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 183 associations by consensus.

OR4F5 by SLC26A9 expression — BREAST

Explore this box plot interactively →