SLC26A8

Across TCGA patient cohorts, SLC26A8 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,544 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC26A8-associated proteins across cancer lineages are PLEKHA6_S459, PLEKHA6_S777, and DDAH1. Each is linked with SLC26A8 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC26A8-to-partner and partner-to-SLC26A8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC26A8 versus PLEKHA6_S459 in PDAC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A8→partner) and Y-score (partner→SLC26A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PLEKHA6_S459 →	+1.209	+0.523	<.001	<.001	3	5
PDAC	PLEKHA6_S777 →	+0.802	+0.433	<.001	<.001	3	5
HNSC	DDAH1 →	+0.628	+0.508	<.001	.001	3	5
UCEC	TMEM63A →	+0.694	+0.551	<.001	.008	3	5
LUAD	PIGR →	+0.719	+0.404	.007	<.001	3	4
UCEC	RAB27B →	+0.668	+0.531	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,544 associations by consensus.

SLC26A8 vs PLEKHA6_S459 — PDAC

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