Across TCGA patient cohorts, SLC26A6 protein abundance is significantly associated with the RNA expression of many other genes, with 8,722 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC26A6-associated genes across cancer lineages are COL4A4, HELB, and MFF-DT. Each is linked with SLC26A6 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC26A6-to-partner and partner-to-SLC26A6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A6→partner) and Y-score (partner→SLC26A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	COL4A4 →	-1.118	-0.611	<.001	<.001	3	5
UCEC	HELB →	-0.648	-0.614	<.001	<.001	3	4
LUAD	MFF-DT →	-0.731	-0.547	<.001	<.001	3	4
LSCC	ZNF737 →	-0.922	-0.445	<.001	<.001	3	4
OV	TRAK2 →	-0.881	-1.423	<.001	.002	3	3
HNSC	RIN3 →	-0.573	-0.405	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,722 associations by consensus.

Exploration

SLC26A6 survival (RNA) · tumor vs normal (RNA) · all SLC26A6 data types