Across TCGA patient cohorts, SLC26A6 mutation is significantly associated with the RNA expression of many other genes, with 2,233 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A6-associated genes across cancer lineages are MIR3681, RN7SKP231, and RN7SL741P. Each is linked with SLC26A6 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC26A6-to-partner and partner-to-SLC26A6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A6→partner) and Y-score (partner→SLC26A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR3681 →	+0.260	+7.471	<.001	.008	3	4
COAD	RN7SKP231 →	+0.571	+4.666	<.001	.005	3	3
COAD	RN7SL741P →	+0.483	+4.537	<.001	.006	3	3
COAD	NDUFS5P6 →	+0.256	+4.962	<.001	.003	3	3
COAD	RNU6-711P →	+1.404	+4.484	<.001	.002	3	2
COAD	RNU6-666P →	+0.787	+6.149	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,233 associations by consensus.

Exploration

SLC26A6 survival (RNA) · tumor vs normal (RNA) · all SLC26A6 data types