Across TCGA cell cohorts, SLC26A6 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC26A6-associated genes across cancer lineages are KIR2DL1, C4orf17, and LRIT1. Each is linked with SLC26A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC26A6-to-partner and partner-to-SLC26A6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A6→partner) and Y-score (partner→SLC26A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KIR2DL1 →	+0.061	+4.359	<.001	<.001	3	1
BLOOD_Leukemia	C4orf17 →	+0.060	+4.091	<.001	.002	3	1
BLOOD_Leukemia	LRIT1 →	+0.030	+3.684	<.001	.004	3	1
BLOOD_Leukemia	MS4A5 →	+0.040	+3.969	<.001	.009	3	1
BLOOD_Leukemia	KIR3DL1 →	+0.023	+3.691	.002	.002	3	1
BLOOD_Leukemia	OR1N1 →	+0.056	+3.234	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration

SLC26A6 survival (RNA) · tumor vs normal (RNA) · all SLC26A6 data types