SLC26A3

Across TCGA patient cohorts, SLC26A3 mutation is significantly associated with the total protein of many other genes, with 67 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A3-associated genes across cancer lineages are INPP4B, Rad50, and c-Met_pY1235. Each is linked with SLC26A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC26A3-to-partner and partner-to-SLC26A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by SLC26A3-low versus SLC26A3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A3→partner) and Y-score (partner→SLC26A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.551	-3.169	.001	.017	3	3
UCEC	Rad50 →	-0.189	-1.440	.024	.024	3	3
UCEC	c-Met_pY1235 →	+0.058	+1.440	.025	.024	3	3
SKCM	Src →	-0.218	-1.999	.007	.002	3	2
UCEC	Bcl-2 →	-0.297	-1.874	.013	.049	3	2
COAD	EGFR_pY1068 →	-0.414	-2.987	.007	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

INPP4B by SLC26A3 expression — COAD

Explore this box plot interactively →