SLC26A2

Across TCGA patient cohorts, SLC26A2 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC26A2-associated genes across cancer lineages are PCNA, EGFR_pY1068, and eIF4G. Each is linked with SLC26A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC26A2-to-partner and partner-to-SLC26A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by SLC26A2-low versus SLC26A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A2→partner) and Y-score (partner→SLC26A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.238	+3.321	.004	.009	3	2
UCEC	EGFR_pY1068 →	-0.247	-1.807	.010	.025	3	1
UCEC	eIF4G →	+0.299	+3.321	.012	.009	3	1
UCEC	Heregulin →	-0.119	-1.700	.012	.042	3	1
UCEC	INPP4B →	-0.258	-2.584	.037	.010	3	1
UCEC	JNK_pT183_Y185 →	-0.189	-2.584	.003	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

PCNA by SLC26A2 expression — UCEC

Explore this box plot interactively →