SLC26A2

Across TCGA cell cohorts, SLC26A2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC26A2-associated genes across cancer lineages are TAAR8, OR4F5, and ACER1. Each is linked with SLC26A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC26A2-to-partner and partner-to-SLC26A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR8 grouped by SLC26A2-low versus SLC26A2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A2→partner) and Y-score (partner→SLC26A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TAAR8 →	+0.022	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR4F5 →	+0.012	+4.887	<.001	.009	3	1
LARGE_INTESTINE	ACER1 →	+0.167	+3.823	<.001	.006	3	1
LARGE_INTESTINE	HNRNPCL4 →	+0.051	+3.793	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TAAR8 by SLC26A2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →