SLC25A6

Across TCGA pan-cancer cohorts, SLC25A6 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC25A6 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC25A6 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC25A6 expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

LUAD, CCRCC, and GBM are the cancer types where SLC25A6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.685	0.309	<.001	26	view →
CCRCC	OS	Quartile	III,IV	0.212	1.000	.038	6	view →
GBM	OS	Median	All	0.954	0.767	.014	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC25A6–LUAD (DFS)

Open the LUAD breakdown →