SLC25A6

Across TCGA patient cohorts, SLC25A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,141 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SLC25A6-associated GO terms across cancer lineages are tRNA thio-modification, Protein localization to endoplasmic reticulum, and Maintenance of location in cell. Each is linked with SLC25A6 in more than 16 cancer types. Because this analysis shows association rather than direction, both SLC25A6-to-partner and partner-to-SLC25A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA thio-modification grouped by SLC25A6-low versus SLC25A6-high in READ.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A6→partner) and Y-score (partner→SLC25A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	tRNA thio-modification →	+0.046	+0.565	<.001	<.001	3	17
STAD	Protein localization to endoplasmic reticulum →	-0.048	-0.421	<.001	<.001	3	16
STAD	Maintenance of location in cell →	-0.033	-0.425	<.001	<.001	3	15
THYM	Intracellular corticosteroid receptor signaling pathway →	-0.050	-0.303	<.001	<.001	3	15
UVM	Negative regulation of viral genome replication →	-0.056	-0.715	<.001	<.001	3	15
SCLC	Cytoplasmic pattern recognition receptor signaling pathway →	-0.049	-0.577	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,141 associations by consensus.

tRNA thio-modification by SLC25A6 expression — READ

Explore this box plot interactively →