SLC25A6

Across TCGA patient cohorts, SLC25A6 mutation is significantly associated with the RNA expression of many other genes, with 4,082 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A6-associated genes across cancer lineages are EEF1E1-BLOC1S5, MIR6894, and RN7SL47P. Each is linked with SLC25A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A6-to-partner and partner-to-SLC25A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EEF1E1-BLOC1S5 grouped by SLC25A6-low versus SLC25A6-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A6→partner) and Y-score (partner→SLC25A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	EEF1E1-BLOC1S5 →	+0.052	+4.969	<.001	.004	3	2
UCEC	MIR6894 →	+0.417	+1.730	.002	.003	3	2
SKCM	RN7SL47P →	+0.168	+5.037	<.001	.009	3	2
CESC	TRAJ12 →	+0.736	+4.193	<.001	.009	3	2
COAD	PAWRP1 →	+0.341	+3.841	<.001	.005	3	2
LUAD	RN7SL429P →	+0.220	+5.279	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,082 associations by consensus.

EEF1E1-BLOC1S5 by SLC25A6 expression — CESC

Explore this box plot interactively →