SLC25A6

Across TCGA cell cohorts, SLC25A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,005 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC25A6-associated GO terms across cancer lineages are Mitochondrial ADP transmembrane transport, Metanephric proximal tubule development, and Energy coupled proton transmembrane transport, against electrochemical gradient. Each is linked with SLC25A6 in more than 12 cancer types. Because this analysis shows association rather than direction, both SLC25A6-to-partner and partner-to-SLC25A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial ADP transmembrane transport grouped by SLC25A6-low versus SLC25A6-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A6→partner) and Y-score (partner→SLC25A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Mitochondrial ADP transmembrane transport →	+0.162	+1.421	<.001	<.001	3	13
STOMACH	Metanephric proximal tubule development →	+0.235	+1.060	.004	.003	2	11
LUNG_SCLC	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.071	+1.188	<.001	<.001	3	9
LUNG_SCLC	Electron transport coupled proton transport →	+0.071	+1.188	<.001	<.001	3	9
URINARY_TRACT	Enzyme-directed rRNA pseudouridine synthesis →	+0.089	+0.791	.006	.009	2	9
SOFT_TISSUE	Vesicle uncoating →	+0.101	+0.631	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,005 associations by consensus.

Mitochondrial ADP transmembrane transport by SLC25A6 expression — OESOPHAGUS

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