SLC25A53

Across TCGA patient cohorts, SLC25A53 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,494 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SLC25A53-associated proteins across cancer lineages are MRPS5, SEPTIN7, and TBRG4. Each is linked with SLC25A53 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC25A53-to-partner and partner-to-SLC25A53 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC25A53 versus MRPS5 in OV, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A53→partner) and Y-score (partner→SLC25A53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MRPS5 →	-0.470	-0.416	<.001	<.001	3	7
PDAC	SEPTIN7 →	+0.245	+0.223	<.001	<.001	3	6
COAD	TBRG4 →	-0.409	-0.233	<.001	.001	3	6
COAD	HDGFL3 →	+0.470	+0.178	<.001	.005	3	6
OV	XPNPEP3 →	-0.362	-0.342	.008	.002	3	6
PDAC	PPP1R12C →	+0.255	+0.367	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,494 associations by consensus.

SLC25A53 vs MRPS5 — OV

Explore this scatter interactively →