SLC25A53

Across TCGA patient cohorts, SLC25A53 protein abundance is significantly associated with the RNA expression of many other genes, with 1,040 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC25A53-associated genes across cancer lineages are LGALS1, RASL10A, and CD40. Each is linked with SLC25A53 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A53-to-partner and partner-to-SLC25A53 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC25A53 versus LGALS1 in GBM, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A53→partner) and Y-score (partner→SLC25A53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LGALS1 →	-0.779	-0.431	.004	.007	3	1
GBM	RASL10A →	+0.588	+0.343	.001	.003	3	1
GBM	CD40 →	-0.751	-0.419	<.001	.002	3	1
GBM	SLC17A9 →	-0.536	-0.465	.007	.002	3	1
GBM	HTATSF1 →	+0.295	+0.335	.001	.004	3	1
GBM	TIMP1 →	-1.242	-0.496	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,040 associations by consensus.

SLC25A53 vs LGALS1 — GBM

Explore this scatter interactively →