SLC25A53

Across TCGA cell cohorts, SLC25A53 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,734 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A53-associated GO terms across cancer lineages are NAD transmembrane transport, NAD transport, and Regulation of DNA-templated transcription initiation. Each is linked with SLC25A53 in more than 16 cancer types. Because this analysis shows association rather than direction, both SLC25A53-to-partner and partner-to-SLC25A53 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NAD transmembrane transport grouped by SLC25A53-low versus SLC25A53-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A53→partner) and Y-score (partner→SLC25A53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	NAD transmembrane transport →	+0.128	+0.870	<.001	<.001	3	17
LUNG_SCLC	NAD transport →	+0.128	+0.870	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated transcription initiation →	+0.058	+0.646	.001	.005	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.063	+0.585	.001	.005	3	10
PANCREAS	Mitotic spindle elongation →	+0.212	+0.724	<.001	<.001	3	10
PANCREAS	Mitotic spindle midzone assembly →	+0.212	+0.724	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,734 associations by consensus.

NAD transmembrane transport by SLC25A53 expression — LUNG_SCLC

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