SLC25A53

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC25A53 protein abundance is significantly associated with the RNA expression of many other genes, with 1,083 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible SLC25A53-associated genes across cancer lineages are BTBD9, HM13, and LYSMD4. Each is linked with SLC25A53 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC25A53-to-partner and partner-to-SLC25A53 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC25A53 versus BTBD9 in LIVER, with a Pearson correlation of -0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A53→partner) and Y-score (partner→SLC25A53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIVERBTBD9 →-0.757-1.450.002<.00135
LARGE_INTESTINEHM13 →+1.057+1.459.001.00134
LIVERLYSMD4 →+1.580+1.347.001.00134
BLOOD_MyelomaDNAI4 →-0.720-1.165.004<.00133
LARGE_INTESTINESPCS2 →+0.740+1.446.006.00233
LARGE_INTESTINEANKHD1 →+0.777+1.617.004.00533
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,083 associations by consensus.

SLC25A53 vs BTBD9 — LIVER

Per-sample scatter of SLC25A53 vs BTBD9 in LIVER (Pearson r = -0.67).

Explore this scatter interactively →

Exploration