SLC25A52

Across TCGA patient cohorts, SLC25A52 mutation is significantly associated with the RNA expression of many other genes, with 2,503 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A52-associated genes across cancer lineages are C1orf174, NAP1L4, and RBBP8. Each is linked with SLC25A52 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A52-to-partner and partner-to-SLC25A52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf174 grouped by SLC25A52-low versus SLC25A52-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A52→partner) and Y-score (partner→SLC25A52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C1orf174 →	+0.404	+2.008	.001	.005	3	3
UCEC	NAP1L4 →	+0.357	+2.649	<.001	.005	3	3
SKCM	RBBP8 →	+0.784	+2.328	.001	.003	3	3
UCEC	NCAPG →	+0.826	+3.818	<.001	<.001	3	3
SKCM	FIG4 →	+0.481	+2.710	.008	.003	3	3
UCEC	SRSF4 →	+0.432	+2.807	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,503 associations by consensus.

C1orf174 by SLC25A52 expression — UCEC

Explore this box plot interactively →