SLC25A52

Across TCGA cell cohorts, SLC25A52 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC25A52-associated genes across cancer lineages are OR10K1, OR10K2, and TIFAB. Each is linked with SLC25A52 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A52-to-partner and partner-to-SLC25A52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10K1 grouped by SLC25A52-low versus SLC25A52-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A52→partner) and Y-score (partner→SLC25A52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR10K1 →	+0.569	+5.029	<.001	.006	3	1
LUNG_SCLC	OR10K2 →	+0.026	+5.643	<.001	.002	3	1
SKIN	TIFAB →	+0.006	+5.415	<.001	.004	3	1
BLOOD_Leukemia	CT45A6 →	+0.189	+4.922	<.001	.009	3	1
BLOOD_Lymphoma	MT1B →	+1.172	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	RESP18 →	+0.042	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR10K1 by SLC25A52 expression — LUNG_SCLC

Explore this box plot interactively →