SLC25A51P3

Across TCGA pan-cancer cohorts, SLC25A51P3 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated SLC25A51P3 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SLC25A51P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC25A51P3 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUAD show a favorable association.

KIRC, SKCM, and UVM are the cancer types where SLC25A51P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.444	0.662	.021	39	view →
SKCM	OS	Tertile	IV	0.179	0.755	<.001	30	view →
UVM	OS	Tertile	All	0.327	0.728	.002	30	view →
BLCA	DFS	Tertile	IV	0.173	0.489	.001	27	view →
MESO	OS	Tertile	II,III,IV	0.197	0.575	.040	18	view →
ACC	DFS	Tertile	All	0.068	0.623	.015	18	view →
ESCA	OS	Tertile	III,IV	0.594	0.300	.021	17	view →
LUAD	DFS	Tertile	III,IV	0.891	0.461	.017	15	view →
HNSC	OS	Tertile	All	0.906	0.738	.016	15	view →
LGG	OS	Tertile	All	0.195	0.477	.016	9	view →
UCEC	DFS	Tertile	All	0.754	0.846	.044	6	view →
KIRP	OS	Tertile	All	0.273	0.716	.027	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

SLC25A51P3–KIRC (DFS)

Open the KIRC breakdown →