Across TCGA pan-cancer cohorts, SLC25A51P1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC25A51P1 data layer compared with 13 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher SLC25A51P1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC25A51P1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

LUSC, UCEC, and LIHC are the cancer types where SLC25A51P1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	II,III,IV	0.079	0.750	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LIHC	DFS	Median	All	0.052	0.531	<.001	5	view →
KIRP	OS	Median	II,III,IV	0.199	0.771	.030	4	view →
HNSC	OS	Median	IV	1.000	0.337	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: SLC25A51P1 tumor-vs-normal RNA expression · all SLC25A51P1 data types