SLC25A51

Across TCGA patient cohorts, SLC25A51 mutation is significantly associated with the RNA expression of many other genes, with 930 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A51-associated genes across cancer lineages are ARF4P1, DOC2B, and ZNHIT3. Each is linked with SLC25A51 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A51-to-partner and partner-to-SLC25A51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARF4P1 grouped by SLC25A51-low versus SLC25A51-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A51→partner) and Y-score (partner→SLC25A51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARF4P1 →	+0.585	+3.254	<.001	.008	3	1
UCEC	DOC2B →	-1.310	-2.700	<.001	.006	3	1
UCEC	ZNHIT3 →	+0.447	+3.828	.008	<.001	3	1
UCEC	TAF9 →	+0.693	+3.459	<.001	.005	3	1
UCEC	PRAG1 →	+0.710	+3.202	.009	.009	3	1
UCEC	TUBGCP5 →	+0.490	+2.732	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 930 associations by consensus.

ARF4P1 by SLC25A51 expression — UCEC

Explore this box plot interactively →