SLC25A51

Across TCGA patient cohorts, SLC25A51 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A51-associated genes across cancer lineages are Ku80, p38-MAPK_pT180_Y182, and SCD. Each is linked with SLC25A51 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A51-to-partner and partner-to-SLC25A51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by SLC25A51-low versus SLC25A51-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A51→partner) and Y-score (partner→SLC25A51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.242	+1.887	.028	.031	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.500	-2.571	.017	.011	3	1
UCEC	SCD →	+0.125	+2.179	.014	.034	3	1
UCEC	Src_pY527 →	-0.516	-2.999	.010	.035	3	1
UCEC	STAT3_pY705 →	-0.580	-2.584	<.001	.010	3	1
UCEC	Cyclin-E2 →	+0.177	+2.584	.024	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Ku80 by SLC25A51 expression — UCEC

Explore this box plot interactively →