SLC25A47

Across TCGA patient cohorts, SLC25A47 mutation is significantly associated with the RNA expression of many other genes, with 236 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SLC25A47-associated genes across cancer lineages are IFNA10, RNU6-165P, and MARK2P12. Each is linked with SLC25A47 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A47-to-partner and partner-to-SLC25A47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA10 grouped by SLC25A47-low versus SLC25A47-high in SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A47→partner) and Y-score (partner→SLC25A47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	IFNA10 →	+0.101	+4.847	<.001	.009	3	3
HNSC	RNU6-165P →	+0.345	+5.936	<.001	.001	3	3
LUAD	MARK2P12 →	+0.147	+4.575	<.001	.001	3	2
SKCM	RPSAP37 →	+0.018	+3.282	<.001	.005	3	2
CESC	NF1P3 →	+0.473	+4.669	<.001	.007	3	2
HNSC	MIR520C →	+0.387	+4.655	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 236 associations by consensus.

IFNA10 by SLC25A47 expression — SCLC

Explore this box plot interactively →