SLC25A47

Across TCGA patient cohorts, SLC25A47 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SLC25A47-associated genes across cancer lineages are Tuberin_pT1462, N-Ras, and PI3K-p85. Each is linked with SLC25A47 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A47-to-partner and partner-to-SLC25A47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tuberin_pT1462 grouped by SLC25A47-low versus SLC25A47-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A47→partner) and Y-score (partner→SLC25A47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Tuberin_pT1462 →	+0.352	+3.000	.015	.035	3	2
SKCM	N-Ras →	-0.177	-3.321	.012	.010	3	1
SKCM	PI3K-p85 →	+0.350	+2.820	.001	.035	3	1
SKCM	STAT5a →	+0.699	+2.824	.014	.034	3	1
SKCM	CD49b →	-0.350	-3.000	.004	.035	2	1
SKCM	PEA-15_pS116 →	+0.343	+3.321	.025	.010	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Tuberin_pT1462 by SLC25A47 expression — SKCM

Explore this box plot interactively →