SLC25A47

Across TCGA cell cohorts, SLC25A47 mutation is significantly associated with the RNA expression of many other genes, with 767 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A47-associated genes across cancer lineages are C6orf118, HHLA1, and SLC22A3. Each is linked with SLC25A47 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A47-to-partner and partner-to-SLC25A47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by SLC25A47-low versus SLC25A47-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A47→partner) and Y-score (partner→SLC25A47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.095	+2.015	<.001	.005	3	2
BLOOD_Leukemia	HHLA1 →	+0.009	+3.551	<.001	.009	3	1
BLOOD_Leukemia	SLC22A3 →	+0.078	+4.037	<.001	.004	3	1
BLOOD_Leukemia	OR1G1 →	+0.063	+3.705	<.001	.007	3	1
BLOOD_Leukemia	CCT8L2 →	+0.009	+3.874	<.001	.005	3	1
BLOOD_Leukemia	HSD3B2 →	+0.034	+4.339	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 767 associations by consensus.

C6orf118 by SLC25A47 expression — LARGE_INTESTINE

Explore this box plot interactively →