SLC25A46

Across TCGA patient cohorts, SLC25A46 mutation is significantly associated with the RNA expression of many other genes, with 1,195 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A46-associated genes across cancer lineages are RN7SL447P, OR4G4P, and MIR103A1. Each is linked with SLC25A46 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A46-to-partner and partner-to-SLC25A46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL447P grouped by SLC25A46-low versus SLC25A46-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A46→partner) and Y-score (partner→SLC25A46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL447P →	+0.519	+4.537	<.001	.006	3	3
SKCM	OR4G4P →	+0.029	+4.147	<.001	.008	3	3
COAD	MIR103A1 →	+0.984	+5.136	<.001	.002	3	2
COAD	RNU6-661P →	+0.767	+4.666	<.001	.005	3	2
COAD	RN7SKP103 →	+0.977	+4.418	<.001	.008	3	2
COAD	RNA5SP363 →	+0.845	+5.375	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,195 associations by consensus.

RN7SL447P by SLC25A46 expression — COAD

Explore this box plot interactively →