SLC25A46

Across TCGA cell cohorts, SLC25A46 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,934 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A46-associated GO terms across cancer lineages are Positive regulation of translational initiation, Regulation of angiotensin-activated signaling pathway, and Endocytic recycling. Each is linked with SLC25A46 in more than 11 cancer types. Because this analysis shows association rather than direction, both SLC25A46-to-partner and partner-to-SLC25A46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of translational initiation grouped by SLC25A46-low versus SLC25A46-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A46→partner) and Y-score (partner→SLC25A46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of translational initiation →	+0.115	+0.797	.003	.005	2	12
URINARY_TRACT	Regulation of angiotensin-activated signaling pathway →	+0.136	+0.692	.005	<.001	3	11
BONE	Endocytic recycling →	+0.061	+0.656	.006	.004	3	10
BONE	Piecemeal microautophagy of the nucleus →	+0.086	+0.896	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of meiotic cell cycle →	+0.071	+0.811	.007	.006	3	10
URINARY_TRACT	Regulation of microtubule cytoskeleton organization →	+0.063	+0.916	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,934 associations by consensus.

Positive regulation of translational initiation by SLC25A46 expression — LIVER

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