SLC25A45

Across TCGA pan-cancer cohorts, SLC25A45 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC25A45 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SLC25A45 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLC25A45 expression acts as an unfavorable survival marker.

STAD, COAD, and ESCA are the cancer types where SLC25A45 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.359	0.670	<.001	36	view →
COAD	DFS	Median	All	0.153	0.794	<.001	16	view →
ESCA	DFS	Median	All	0.075	0.533	.003	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC25A45–STAD (OS)

Open the STAD breakdown →