SLC25A45

Across TCGA patient cohorts, SLC25A45 mutation is significantly associated with the RNA expression of many other genes, with 292 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A45-associated genes across cancer lineages are RNU6-959P, KRTAP12-4, and OR7E23P. Each is linked with SLC25A45 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A45-to-partner and partner-to-SLC25A45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-959P grouped by SLC25A45-low versus SLC25A45-high in THCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A45→partner) and Y-score (partner→SLC25A45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	RNU6-959P →	+0.441	+6.772	<.001	<.001	3	1
THCA	KRTAP12-4 →	+0.158	+5.191	<.001	.007	3	1
THCA	OR7E23P →	+0.042	+5.312	<.001	.006	3	1
THCA	LINC00410 →	+0.037	+5.024	<.001	.009	3	1
THCA	IFNA13 →	+0.070	+5.312	<.001	.006	3	1
THCA	H3P41 →	+0.157	+5.921	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 292 associations by consensus.

RNU6-959P by SLC25A45 expression — THCA

Explore this box plot interactively →