SLC25A45

Across TCGA patient cohorts, SLC25A45 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A45-associated genes across cancer lineages are Mesangial cells, mv Endothelial cells, and CD8+ naive T-cells. Each is linked with SLC25A45 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A45-to-partner and partner-to-SLC25A45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by SLC25A45-low versus SLC25A45-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A45→partner) and Y-score (partner→SLC25A45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mesangial cells →	-0.051	-3.448	.008	.005	3	1
UCEC	mv Endothelial cells →	-0.025	-2.311	.031	.036	2	1
UCEC	CD8+ naive T-cells →	+0.036	+3.502	.007	.002	1	1
UCEC	Endothelial cells →	-0.044	-2.279	.021	.036	1	1
UCEC	lymphatic Endothelial cells →	-0.025	-3.405	.039	.005	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Mesangial cells by SLC25A45 expression — UCEC

Explore this box plot interactively →