SLC25A45

Across TCGA cell cohorts, SLC25A45 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,278 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC25A45-associated GO terms across cancer lineages are Cytosolic transport, Glycerophospholipid metabolic process, and Positive regulation of intracellular estrogen receptor signaling pathway. Each is linked with SLC25A45 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC25A45-to-partner and partner-to-SLC25A45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by SLC25A45-low versus SLC25A45-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A45→partner) and Y-score (partner→SLC25A45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.062	+0.865	<.001	<.001	3	10
PANCREAS	Glycerophospholipid metabolic process →	+0.049	+1.153	<.001	.002	3	10
LUNG_NSCLC_LUAD	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.121	+1.140	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of alternative mRNA splicing, via spliceosome →	+0.090	+0.819	<.001	<.001	3	9
LARGE_INTESTINE	Regulation of DNA-templated transcription initiation →	+0.048	+0.751	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA-templated transcription initiation →	+0.073	+0.930	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,278 associations by consensus.

Cytosolic transport by SLC25A45 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →