SLC25A45

Across TCGA cell cohorts, SLC25A45 mutation is significantly associated with the RNA expression of many other genes, with 792 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A45-associated genes across cancer lineages are TAB1, TNRC6B, and SGSM3. Each is linked with SLC25A45 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A45-to-partner and partner-to-SLC25A45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAB1 grouped by SLC25A45-low versus SLC25A45-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A45→partner) and Y-score (partner→SLC25A45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TAB1 →	+0.574	+3.067	.004	.009	3	1
LARGE_INTESTINE	TNRC6B →	+0.701	+3.502	.002	.001	3	1
LARGE_INTESTINE	SGSM3 →	+0.691	+3.502	.002	.001	3	1
LARGE_INTESTINE	ST13 →	+0.471	+3.169	.007	.009	3	1
LARGE_INTESTINE	L3MBTL2 →	+0.779	+3.502	<.001	.001	3	1
LARGE_INTESTINE	PSMC6 →	+0.473	+2.451	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 792 associations by consensus.

TAB1 by SLC25A45 expression — LARGE_INTESTINE

Explore this box plot interactively →