SLC25A42

Across TCGA patient cohorts, SLC25A42 mutation is significantly associated with the RNA expression of many other genes, with 2,276 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A42-associated genes across cancer lineages are MIR4285, OR51C1P, and RNU6-1127P. Each is linked with SLC25A42 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A42-to-partner and partner-to-SLC25A42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4285 grouped by SLC25A42-low versus SLC25A42-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A42→partner) and Y-score (partner→SLC25A42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4285 →	+0.653	+4.450	<.001	.002	3	2
LUAD	OR51C1P →	+0.267	+5.584	<.001	.002	3	2
COAD	RNU6-1127P →	+0.320	+4.721	.001	.004	3	2
UCEC	EIF3JP1 →	+0.141	+2.105	.004	.006	3	2
SKCM	MIR3619 →	+0.431	+3.765	<.001	.007	3	2
BLCA	MIR5093 →	+0.836	+5.996	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,276 associations by consensus.

MIR4285 by SLC25A42 expression — CESC

Explore this box plot interactively →